Han, Sung Nim

Profile

  • Name: Han, Sung Nim
  • Current Position: Professor
  • Major: Clinical Nutrition and Nutritional Immunology
  • Research Areas: Relationship between obesity and immune function, Effects of vitamin D on immune cell differentiation and function, Effects of dietary fat on immune and inflammatory responses, Effects of obesity on mineral and vitamin metabolisms, Precision nutrition
  • Office: +82-2-880-6836
  • E-mail: shhan@snu.ac.kr 

Education

  • 1983.3-1987.2 Food and Nutrition, Seoul National University, BS
  • 1988.3-1990.2 Food and Nutrition, Seoul National University, MS
  • 1993.9-1999.5 Tufts University (Ph.D.) 

Employment/Experience

  • 2016. 3-present Professor, Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
  • 2014.7-2016.7 Deputy Vice President of Student Affairs, Seoul National University
  • 2013.9-2014.8 Visiting Scientist, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
  • 2011.9-2016.8 Associate Professor, Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
  • 2007.9-2011.8 Assistant Professor, Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
  • 2004.6-2007.8 Scientist II, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
  • 2003.11-2007.8 Assistant Professor, The Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University, Boston, MA, USA
  • 2002.2-2004.6 Scientist III, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
  • 2000.9– 2002.1 Research Associate, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
  • 1999.10–2000.8 Dietetic Intern, Brigham and Women’s Hospital, Boston, MA, USA 

Recent Publications

  • AJ Lee, KJ Jeon, MS Kim, H-K Kim, SN Han. Modest weight loss through a 12-week weight management program with behavioral modification seems to attenuate inflammatory responses in young obese Koreans. Nutrition Research 35(4):301-308, 2015.
  • M-H Kim, JN Kim, SN Han, H-K Kim. Ursolic acid isolated from guava leaves inhibits inflammatory mediators and reactive oxygen species in LPS-stimulated macrophages. Immunopharmacology and Immunotoxicology 37(3):228-235, 2015.
  • JM Park, CY Park, SN Han. High fat diet-induced obesity alters vitamin D metabolizing enzyme expression in mice. BioFactors 41(3): 175-182, 2015.
  • S Park, S Shin, Y Lim, JH Shin, JK Seong, SN Han. Korean pine nut oil attenuated hepatic triacylglycerol accumulation in high-fat diet-induced obese mice. Nutrients 8;59 doi:10.3390/nu8010059, 2016.
  • AR Lee, SN Han. Pinolenic Acid Downregulates Lipid Anabolic Pathway in HepG2 Cells. Lipids 51(7): 847-855, 2016.
  • H Chung, D Wu, D Smith, SN Meydani, SN Han. Lower hepatic iron storage associated with obesity in mice can be restored by decreasing body fat mass through feeding a low- fat diet. Nutrition Research 36(9):955-963, 2016.
  • CH Jin, YK So, SN Han, JB Kim. Isoegomaketone upregulates heme oxygenase-1 in RAW264.7 cells via ROS/p38 MAPK/Nrf2 pathway. Biomolecules & Therapeutics 24(5): 510-516, 2016.
  • S Zhu, S Park, Y Lim, S Shin, SN Han. Korean Pine Nut Oil Replacement Decreases Intestinal Lipid Uptake While Improves Hepatic Lipid Metabolism in High Fat Diet Fed Mice. Nutrition Research and Practice 10(5):477-486, 2016.
  • Y Kim, SN Han. Associations between exposure to unhealthy food outlets within residential district and obesity: Using data from 2013 Census on Establishments and 2013-2014 Korea National Health and Nutrition Examination Survey. Korean Journal of Community Nutrition 21(5): 463-476, 2016.
  • CY Park, J Chung, K-O Koo, MS Kim, SN Han. Hepatic iron storage is related to body adiposity and hepatic inflammation. Nutrition & Metabolism 14:14, 2017. (DOI 10.1186/s12986-017-0169-3)
  • CH Jin, HC Park, Y So, B Nam, SN Han, J-B Kim. Comparison of the anti-inflammatory activities of supercritical carbon dioxide versus ethanol extracts from leaves of Perilla frutescens Britt. radiation mutant. Molecules 22(2):311, 2017. (DOI 10.3390/molecules22020311)
  • A Yoon, SA Tammen, S Park, SN Han, SW Choi. Genome-wide hepatic DNA methylation changes in high fat diet-induced obese mice. Nutrition Research and Practice 11(2):105-113, 2017
  • CY Park, S Park, MS Kim, H-K Kim, SN Han. Effects of mild caloric restriction on lipid metabolism and inflammation in liver and adipose tissue. Biochemical and Biophysical Research Communications 490 (3):636-642, 2017.
  • CH Jin, Y So, B Nam, SN Han, J-B Kim. Isoegomaketone alleviates the development of collagen antibody-induced arthritis in male Balb/c mice. Molecules 22(7):1209, 2017. (DOI:10.3390/molecules22071209)
  • JN Kim, SN Han, TJ Ha, H-K Kim. Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages. Nutrition Research and Practice 11(5):357-364, 2017
  • EJ Dennis, M Kang, SN Han. Relation between beverage consumption pattern and metabolic syndrome among healthy Korean adults. Korean Journal of Community Nutrition 22(5): 441-455, 2017.
  • HK Oh, JY Lee, SW Yoon, WK Eo, SN Han. Prognostic role of serum vitamin B12insolidtumorpatients.Korean Journal of Health Promotion 17(4): 282-288, 2017.
  • HK Oh, JY Lee, WK Eo, SW Yoon, SN Han. Elevated Serum Vitamin B12levelsasaprognosticfactorforsurvivaltimeinmetastaticcancerpatients:Aretrospectivestudy.Nutrition and Cancer, 70(1):37-44, 2018. (DOI:10.1080/01635581.2018.1397711)
  • GY Lee, CY Park, KS Cha, SE Lee, M Pae, SN Han. Differential effects of dietary vitamin D supplementation on natural killer cell activity in lean and obese mice. Journal of Nutritional Biochemistry 2018; 55: 178-184.
  • YS Jung, D Wu, D Smith, SN Meydani, SN Han. Dysregulated 1,25-dihydroxyvitamin D levels in high fat diet-induced obesity can be restored by changing to a lower fat diet in mice. Nutrition Research 53:51-60, 2018.
  • GY Lee, SN Han. The role of vitamin E in immunity. Nutrients 2018; 10: 1614.
  • H-K Kim, SN Han. Vitamin E: Regulatory role on gene and protein expression and metabolomics profiles. IUBMB Life 71(4): 442-455, 2019.
  • Yoo JS, CY Park, YK Seo, SH Woo, DY Kim, SN Han. Vitamin D supplementation partially affects colonic changes in dextran sulfate sodium-induced colitis obese mice but not lean mice. Nutrition Research 67: 90-99, 2019.
  • CH Jin, Y So, H-Y Kim, SN Han, J-BKim. Anti-arthritic activities of supercritical carbon dioxide extract derived from radiation mutant Perilla frutescens var. Crispa in collagen antibody-induced arthritis. Nutrients 11;2959 doi:10.3390/nu1122959, 2019 

Grants

  • Effect of MAX-P consumption on natural killer cell functions and SIgA levels Role: Principle Investigator Funding agency: Univera Inc. Period: 6/15/15-6/14/16
  • Modulation of immune and inflammatory response by alteration of vitamin D status in obesity Role: Principle Investigator Funding agency: National Research Foundation of Korea Period: 11/1/15-10/31/18
  • Modulation of autophagy by obesity and vitamin D and its effects on differentiation and function of immune cells Role: Principle Investigator Funding agency: National Research Foundation of Korea Period: 6/1/18-5/31/21
  • Impact of DTC genetic information disclosure on psychological factors, dietary intake and health-related behavior Role: Principle Investigator Funding agency: Seoul National University Period: 8/1/18-2/29/20
  • Needs assessment and feasibility study for the development of Nutritional Science department in Mongolian National University of Medical Sciences Role: Principle Investigator Funding agency: National Research Foundation of Korea and Korean Ministry of Education Period: 4/1/19-1/31/20